Review





Similar Products

hacat human keratinocyte cell line  (CLS Cell Lines Service GmbH)
98
CLS Cell Lines Service GmbH hacat human keratinocyte cell line
Hacat Human Keratinocyte Cell Line, supplied by CLS Cell Lines Service GmbH, used in various techniques. Bioz Stars score: 98/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/keratinocyte+cells/10__36922_slash_mi026060016-54-3-11?v=CLS+Cell+Lines+Service+GmbH
Average 98 stars, based on 1 article reviews
hacat human keratinocyte cell line - by Bioz Stars, 2026-07
98/100 stars
  Buy from Supplier
keratinocytes  (CLS Cell Lines Service GmbH)
98
CLS Cell Lines Service GmbH keratinocytes
Keratinocytes, supplied by CLS Cell Lines Service GmbH, used in various techniques. Bioz Stars score: 98/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/keratinocyte+cells/10__3390_slash_ph19060808-202-12-14?v=CLS+Cell+Lines+Service+GmbH
Average 98 stars, based on 1 article reviews
keratinocytes - by Bioz Stars, 2026-07
98/100 stars
  Buy from Supplier
vitro experimental design immortalized human keratinocytes  (CLS Cell Lines Service GmbH)
98
CLS Cell Lines Service GmbH vitro experimental design immortalized human keratinocytes
Vitro Experimental Design Immortalized Human Keratinocytes, supplied by CLS Cell Lines Service GmbH, used in various techniques. Bioz Stars score: 98/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/keratinocyte+cells/pm42168426-163-1-11?v=CLS+Cell+Lines+Service+GmbH
Average 98 stars, based on 1 article reviews
vitro experimental design immortalized human keratinocytes - by Bioz Stars, 2026-07
98/100 stars
  Buy from Supplier
human immortalized keratinocyte hacat cells  (CLS Cell Lines Service GmbH)
98
CLS Cell Lines Service GmbH human immortalized keratinocyte hacat cells
Limited selectivity in <t>immortalized</t> normal cells of RES and PAC in HeLa and <t>HaCaT</t> cells. ( A ) IC 50 values for RES in HeLa cervical cancer cells and HaCaT normal <t>keratinocytes</t> at 24 and 48 h. ( B ) IC 50 values for PAC under the same conditions. For both agents, IC 50 values were consistently higher in HaCaT cells compared to HeLa cells at both time points, indicating reduced sensitivity of normal cells. The selectivity index (SI), calculated as IC 50 (HaCaT)/IC 50 (HeLa), exceeded 2 in all conditions (RES: 2.6 and 2.2; PAC: 2.2 and 2.1 at 24 and 48 h, respectively), indicating limited selectivity in immortalized normal cells rather than definitive tumor-specific selectivity. Data are derived from three independent experiments ( n = 3). IC 50 values were calculated by nonlinear regression analysis of dose–response curves. It should be noted that HaCaT cells are immortalized keratinocytes and do not fully represent primary normal cervical epithelial cells.
Human Immortalized Keratinocyte Hacat Cells, supplied by CLS Cell Lines Service GmbH, used in various techniques. Bioz Stars score: 98/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/keratinocyte+cells/pmc13207388-223-9-14?v=CLS+Cell+Lines+Service+GmbH
Average 98 stars, based on 1 article reviews
human immortalized keratinocyte hacat cells - by Bioz Stars, 2026-07
98/100 stars
  Buy from Supplier
cell lines human keratinocytes  (CLS Cell Lines Service GmbH)
98
CLS Cell Lines Service GmbH cell lines human keratinocytes
Limited selectivity in <t>immortalized</t> normal cells of RES and PAC in HeLa and <t>HaCaT</t> cells. ( A ) IC 50 values for RES in HeLa cervical cancer cells and HaCaT normal <t>keratinocytes</t> at 24 and 48 h. ( B ) IC 50 values for PAC under the same conditions. For both agents, IC 50 values were consistently higher in HaCaT cells compared to HeLa cells at both time points, indicating reduced sensitivity of normal cells. The selectivity index (SI), calculated as IC 50 (HaCaT)/IC 50 (HeLa), exceeded 2 in all conditions (RES: 2.6 and 2.2; PAC: 2.2 and 2.1 at 24 and 48 h, respectively), indicating limited selectivity in immortalized normal cells rather than definitive tumor-specific selectivity. Data are derived from three independent experiments ( n = 3). IC 50 values were calculated by nonlinear regression analysis of dose–response curves. It should be noted that HaCaT cells are immortalized keratinocytes and do not fully represent primary normal cervical epithelial cells.
Cell Lines Human Keratinocytes, supplied by CLS Cell Lines Service GmbH, used in various techniques. Bioz Stars score: 98/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/keratinocyte+cells/pm42121406-131-0-5?v=CLS+Cell+Lines+Service+GmbH
Average 98 stars, based on 1 article reviews
cell lines human keratinocytes - by Bioz Stars, 2026-07
98/100 stars
  Buy from Supplier
human immortalized keratinocytes hacat cells  (Procell Inc)
86
Procell Inc human immortalized keratinocytes hacat cells
Limited selectivity in <t>immortalized</t> normal cells of RES and PAC in HeLa and <t>HaCaT</t> cells. ( A ) IC 50 values for RES in HeLa cervical cancer cells and HaCaT normal <t>keratinocytes</t> at 24 and 48 h. ( B ) IC 50 values for PAC under the same conditions. For both agents, IC 50 values were consistently higher in HaCaT cells compared to HeLa cells at both time points, indicating reduced sensitivity of normal cells. The selectivity index (SI), calculated as IC 50 (HaCaT)/IC 50 (HeLa), exceeded 2 in all conditions (RES: 2.6 and 2.2; PAC: 2.2 and 2.1 at 24 and 48 h, respectively), indicating limited selectivity in immortalized normal cells rather than definitive tumor-specific selectivity. Data are derived from three independent experiments ( n = 3). IC 50 values were calculated by nonlinear regression analysis of dose–response curves. It should be noted that HaCaT cells are immortalized keratinocytes and do not fully represent primary normal cervical epithelial cells.
Human Immortalized Keratinocytes Hacat Cells, supplied by Procell Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/keratinocyte+cells/pm42115274-244-11-22?v=Procell+Inc
Average 86 stars, based on 1 article reviews
human immortalized keratinocytes hacat cells - by Bioz Stars, 2026-07
86/100 stars
  Buy from Supplier
human keratinocyte cell line  (CLS Cell Lines Service GmbH)
98
CLS Cell Lines Service GmbH human keratinocyte cell line
Limited selectivity in <t>immortalized</t> normal cells of RES and PAC in HeLa and <t>HaCaT</t> cells. ( A ) IC 50 values for RES in HeLa cervical cancer cells and HaCaT normal <t>keratinocytes</t> at 24 and 48 h. ( B ) IC 50 values for PAC under the same conditions. For both agents, IC 50 values were consistently higher in HaCaT cells compared to HeLa cells at both time points, indicating reduced sensitivity of normal cells. The selectivity index (SI), calculated as IC 50 (HaCaT)/IC 50 (HeLa), exceeded 2 in all conditions (RES: 2.6 and 2.2; PAC: 2.2 and 2.1 at 24 and 48 h, respectively), indicating limited selectivity in immortalized normal cells rather than definitive tumor-specific selectivity. Data are derived from three independent experiments ( n = 3). IC 50 values were calculated by nonlinear regression analysis of dose–response curves. It should be noted that HaCaT cells are immortalized keratinocytes and do not fully represent primary normal cervical epithelial cells.
Human Keratinocyte Cell Line, supplied by CLS Cell Lines Service GmbH, used in various techniques. Bioz Stars score: 98/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/keratinocyte+cells/pmc13204243-190-1-6?v=CLS+Cell+Lines+Service+GmbH
Average 98 stars, based on 1 article reviews
human keratinocyte cell line - by Bioz Stars, 2026-07
98/100 stars
  Buy from Supplier
hacat cells  (CLS Cell Lines Service GmbH)
98
CLS Cell Lines Service GmbH hacat cells
Limited selectivity in <t>immortalized</t> normal cells of RES and PAC in HeLa and <t>HaCaT</t> cells. ( A ) IC 50 values for RES in HeLa cervical cancer cells and HaCaT normal <t>keratinocytes</t> at 24 and 48 h. ( B ) IC 50 values for PAC under the same conditions. For both agents, IC 50 values were consistently higher in HaCaT cells compared to HeLa cells at both time points, indicating reduced sensitivity of normal cells. The selectivity index (SI), calculated as IC 50 (HaCaT)/IC 50 (HeLa), exceeded 2 in all conditions (RES: 2.6 and 2.2; PAC: 2.2 and 2.1 at 24 and 48 h, respectively), indicating limited selectivity in immortalized normal cells rather than definitive tumor-specific selectivity. Data are derived from three independent experiments ( n = 3). IC 50 values were calculated by nonlinear regression analysis of dose–response curves. It should be noted that HaCaT cells are immortalized keratinocytes and do not fully represent primary normal cervical epithelial cells.
Hacat Cells, supplied by CLS Cell Lines Service GmbH, used in various techniques. Bioz Stars score: 98/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/keratinocyte+cells/custom%40300493%4042196164?v=CLS+Cell+Lines+Service+GmbH
Average 98 stars, based on 1 article reviews
hacat cells - by Bioz Stars, 2026-07
98/100 stars
  Buy from Supplier
human keratinocyte cell line hacat  (CLS Cell Lines Service GmbH)
98
CLS Cell Lines Service GmbH human keratinocyte cell line hacat
Limited selectivity in <t>immortalized</t> normal cells of RES and PAC in HeLa and <t>HaCaT</t> cells. ( A ) IC 50 values for RES in HeLa cervical cancer cells and HaCaT normal <t>keratinocytes</t> at 24 and 48 h. ( B ) IC 50 values for PAC under the same conditions. For both agents, IC 50 values were consistently higher in HaCaT cells compared to HeLa cells at both time points, indicating reduced sensitivity of normal cells. The selectivity index (SI), calculated as IC 50 (HaCaT)/IC 50 (HeLa), exceeded 2 in all conditions (RES: 2.6 and 2.2; PAC: 2.2 and 2.1 at 24 and 48 h, respectively), indicating limited selectivity in immortalized normal cells rather than definitive tumor-specific selectivity. Data are derived from three independent experiments ( n = 3). IC 50 values were calculated by nonlinear regression analysis of dose–response curves. It should be noted that HaCaT cells are immortalized keratinocytes and do not fully represent primary normal cervical epithelial cells.
Human Keratinocyte Cell Line Hacat, supplied by CLS Cell Lines Service GmbH, used in various techniques. Bioz Stars score: 98/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/keratinocyte+cells/pm42073272-106-1-6?v=CLS+Cell+Lines+Service+GmbH
Average 98 stars, based on 1 article reviews
human keratinocyte cell line hacat - by Bioz Stars, 2026-07
98/100 stars
  Buy from Supplier

Image Search Results


Limited selectivity in immortalized normal cells of RES and PAC in HeLa and HaCaT cells. ( A ) IC 50 values for RES in HeLa cervical cancer cells and HaCaT normal keratinocytes at 24 and 48 h. ( B ) IC 50 values for PAC under the same conditions. For both agents, IC 50 values were consistently higher in HaCaT cells compared to HeLa cells at both time points, indicating reduced sensitivity of normal cells. The selectivity index (SI), calculated as IC 50 (HaCaT)/IC 50 (HeLa), exceeded 2 in all conditions (RES: 2.6 and 2.2; PAC: 2.2 and 2.1 at 24 and 48 h, respectively), indicating limited selectivity in immortalized normal cells rather than definitive tumor-specific selectivity. Data are derived from three independent experiments ( n = 3). IC 50 values were calculated by nonlinear regression analysis of dose–response curves. It should be noted that HaCaT cells are immortalized keratinocytes and do not fully represent primary normal cervical epithelial cells.

Journal: International Journal of Molecular Sciences

Article Title: A Functional Evaluation of Resveratrol–Paclitaxel Combination Reveals Enhanced Apoptotic Responses in HeLa Cells

doi: 10.3390/ijms27104505

Figure Lengend Snippet: Limited selectivity in immortalized normal cells of RES and PAC in HeLa and HaCaT cells. ( A ) IC 50 values for RES in HeLa cervical cancer cells and HaCaT normal keratinocytes at 24 and 48 h. ( B ) IC 50 values for PAC under the same conditions. For both agents, IC 50 values were consistently higher in HaCaT cells compared to HeLa cells at both time points, indicating reduced sensitivity of normal cells. The selectivity index (SI), calculated as IC 50 (HaCaT)/IC 50 (HeLa), exceeded 2 in all conditions (RES: 2.6 and 2.2; PAC: 2.2 and 2.1 at 24 and 48 h, respectively), indicating limited selectivity in immortalized normal cells rather than definitive tumor-specific selectivity. Data are derived from three independent experiments ( n = 3). IC 50 values were calculated by nonlinear regression analysis of dose–response curves. It should be noted that HaCaT cells are immortalized keratinocytes and do not fully represent primary normal cervical epithelial cells.

Article Snippet: Human cervical carcinoma HeLa cells (ATCC ® CCL-2TM) and human immortalized keratinocyte HaCaT cells (Cell Lines Service, CLS, Cat. No. 300493, Eppelheim, Germany) were used in this study.

Techniques: Derivative Assay